BES 355 | Course Introduction and Application Information - Department of Nutrition and Dietetics

Course Name

Nutrition and İmmune System

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
BES 355	Fall/Spring	3	0	3	4

Prerequisites	None
Course Language	Turkish
Course Type	Elective
Course Level	First Cycle
Mode of Delivery	-
Teaching Methods and Techniques of the Course	Discussion Q&A Lecture / Presentation
National Occupation Classification	-
Course Coordinator	Dr.Öğretim Üyesi RÜKSAN ÇEHRELİ
Course Lecturer(s)	Dr.Öğretim Üyesi NEŞE KAYA Dr.Öğretim Üyesi RÜKSAN ÇEHRELİ
Assistant(s)	Arş.Gör. Merve ÖZEN

Course Objectives	The aim of this course is to provide students with knowledge about the related and characteristics of nutrition and immunity and to teach approaches to causative macro/ micro nutrients and immunity , planning nutritional therapy, and preventing enfections reactions and oto-immunity related disease sensitivities.
Learning Outcomes	The students who succeeded in this course; Will be able to define immune system cells and their basic characteristics. Will be able to explain the activities of immune system cells and the effects of nutrients required for rapidly proliferating cells based on current knowledge. Will be able to explain the roles of immune system cells in protecting the body against diseases. Will be able to define immunotherapy models used in the treatment of certain diseases.
Course Description	This course covers the characteristics and functions of immune system cells and examines the roles of macronutrients and micronutrients associated with these functions. It also explores the effects of nutrition on the immune system and its role in disease prevention and treatment based on current evidence.
Related Sustainable Development Goals

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Management Skills Courses
	Transferable Skill Courses

Week	Subjects	Related Preparation
1	What is the immune system? Definition of the immune system, basic concepts, and immune system organs (lymphoid organs).	Gershwin, M. E., Nestel, P., & Keen, C. L. (Eds.). (2004). Handbook of nutrition and immunity. Springer Science & Business Media
2	What are immune system cells? Functions of the immune system; innate and adaptive immune responses.	2025 Nobel Fizyoloji ve Tıp Ödülü: Bizİ bizden koruyan hücrelerimiz Emin Kansu 4 Aralık 2025 Sarkaç dergisi
3	Humoral and cellular immunity mechanisms.	Aggarwal, B. B., & Heber, D. (Eds.). (2014). Immunonutrition: Interactions of diet, genetics, and inflammation (1st ed.). CRC Press.
4	What is the adaptive immune system? Acute vs. chronic inflammation	Friedland,J.,Lightstone L. Infection and Immunity,2th Edition,Taylor Francis Group,UK,2004
5	Characterization of the cells involved in these systems and the relationship between chronic inflammation and nutrition: effects of malnutrition on immunity	Gershwin, M. E., Nestel, P., & Keen, C. L. (Eds.). (2004). Handbook of nutrition and immunity. Springer Science & Business Media. Friedland,J.,Lightstone L. Infection and Immunity,2th Edition,Taylor Francis Group,UK,2004
6	Impact of macronutrients (carbohydrates, proteins, fats, and omega-3 fatty acids) on immune functions	Chung J, Vallurupalli M, et al. Sialylated CD43 forms a glyco-immune barrier that restrains anti-leukemic immunity. Science. Online April 9, 2026. DOI: 10.1126/science.ady5196
7	Micronutrients and their roles in immune system cells	Gershwin, M. E., Nestel, P., & Keen, C. L. (Eds.). (2004). Handbook of nutrition and immunity. Springer Science & Business Media
8	Ara Sınav
9	What are the energy sources for immune system cells? Discussion with Case Studies	Gershwin, M. E., Nestel, P., & Keen, C. L. (Eds.). (2004). Handbook of nutrition and immunity. Springer Science & Business Media
10	Diseases associated with immune system deficiency: Various infections. Discussion with Case Studies	Friedland,J.,Lightstone L. Infection and Immunity,2th Edition,Taylor Francis Group,UK,2004
11	Autoimmune diseases (Type 1 diabetes, autoimmune diabetes mellitus), cancer. Discussion with Case Studies	Cehreli Ruksan , Moleculer Nutritional Immunology and Cancer. Journal of Oncological Sciences 4 (1), 40-46, 2018.
12	Autoimmune diseases: Thyroid disorders (Hashimoto's), Discussion with Case Studies	Cehreli Ruksan , Moleculer Nutritional Immunology and Cancer. Journal of Oncological Sciences 4 (1), 40-46, 2018.
13	Autoimmune diseases: Gastrointestinal diseases (ulcerative colitis, IBD, IBS, Crohn's disease). Discussion with Case Studies	Aggarwal, B. B., & Heber, D. (Eds.). (2014). Immunonutrition: Interactions of diet, genetics, and inflammation (1st ed.). CRC Press.
14	Rheumatic diseases (ankylosing spondylitis, ...). Discussion with Case Studies	Aggarwal, B. B., & Heber, D. (Eds.). (2014). Immunonutrition: Interactions of diet, genetics, and inflammation (1st ed.). CRC Press.
15	Semester Review
16	Final exam

Course Notes/Textbooks

Mahan L.K., Escott-Stump S. Krause's Food, Nutrition and Diet Therapy, 10th Edition, W. B. Saunders Company, USA, 2000.
Friedland,J.,Lightstone L. Infection and Immunity,2th Edition,Taylor Francis Group,UK,2004.

Gershwin,E.,Nestel P.,Keen C.Handbook of Nutrition and Immunity,Humana Press,New Jersey,2004.
Watson R.,Zibadi S.,Preedy V.Dietary Components and Immune Function,New Jersey,2010.

Suggested Readings/Materials

Aggarwal, B. B., & Heber, D. (Eds.). (2014). Immunonutrition: Interactions of diet, genetics, and inflammation (1st ed.). CRC Press.

Baysal, A. (2018). Diyet el kitabı. Hatiboğlu Yayınevi.

Cohen, J., Powderly, W. G., & Opal, S. M. (2016). Infectious diseases (E-book). Elsevier Health Sciences.

Gershwin, M. E., Nestel, P., & Keen, C. L. (Eds.). (2004). Handbook of nutrition and immunity. Springer Science & Business Media.

Raymond, J. L., & Morrow, K. (2022). Krause and Mahan’s food & the nutrition care process (16th ed.). Elsevier.

Muscaritoli, M., Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., ... & Bischoff, S. C. (2021). ESPEN practical guideline: Clinical Nutrition in cancer. Clinical nutrition, 40(5), 2898-2913.

Cehreli Ruksan , Moleculer Nutritional Immunology and Cancer. . Journal of Oncological Sciences 4 (1), 40-46, 2018. 17, 2018.

Semester Activities	Number	Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
Presentation / Jury
Project
Seminar / Workshop
Oral Exams	1	10
Midterm	1	30
Final Exam	1	60
Total

Weighting of Semester Activities on the Final Grade	2	40
Weighting of End-of-Semester Activities on the Final Grade	1	60
Total

Semester Activities	Number	Duration (Hours)	Workload
Theoretical Course Hours (Including exam week: 16 x total hours)	16	3	48
Laboratory / Application Hours	16		0
Study Hours Out of Class	14	2	28
Field Work			0
Quizzes / Studio Critiques			0
Portfolio			0
Homework / Assignments			0
Presentation / Jury			0
Project			0
Seminar / Workshop			0
Oral Exam	1	2	2
Midterms	1	12	12
Final Exam	1	15	15
		Total	105

#	Program Competencies/Outcomes	* Contribution Level
#	Program Competencies/Outcomes	1	2	3	4	5
1	Effectively uses evidence-based professional knowledge of basic, health and social sciences required by the dietitian profession throughout their professional life.	-	-	-	-	-
2	Gains the ability to use the acquired knowledge to improve the health level and quality of life of the society.	X	-	-	-	-
3	Gains the ability to work effectively as an individual and to take responsibility in multidisciplinary teamwork.	X	-	-	-	-
4	Identifies, defines, interprets, decides and solves the problems that may be encountered in different fields of Nutrition and Dietetics.	-	-	-	-	-
5	Applies individual-specific professional knowledge in accordance with the physiological, environmental and socio-cultural needs of healthy and/or sick individuals.	-	X	-	-	-
6	Continuously improve themselves in their field by using accurate and reliable information and modern information technologies.	-	X	-	-	-
7	Acquires the ability to communicate verbally and in writing at national and international level on professional issues related to the field of Nutrition and Dietetics.	-	-	-	-	-
8	Acts in accordance with social, scientific and ethical values in the stages of data collection, interpretation and evaluation of results while conducting research in the field of Nutrition and Dietetics.	-	X	-	-	-
9	Acquires knowledge and practical skills in the development of individual and social nutrition recommendations at national and international level, and the establishment of food and nutrition plans and policies.	-	-	-	-	-
10	Acts in accordance with the awareness of professional ethics within the legal framework related to their duties, rights and responsibilities. Sets an example to colleagues and society.	-	X	-	-	-

BES 355 | Course Introduction and Application Information

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

EVALUATION SYSTEM

ECTS / WORKLOAD TABLE

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

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